Models

Baichuan-M3 is a new-generation open-source medical-enhanced language model with 235 billion parameters, built on Qwen3-235B-A22B and released under Apache 2.0 in January 2026.

Large language modelsOpen sourceChina

GWM-1 is Runway's first general world model: an autoregressive system that generates 720p video frame by frame in real time and can be steered with camera pose, robot commands or audio.

MultimodalRoboticsGenerative models

Genie 3 is Google DeepMind's general-purpose world model, announced on 5 August 2025. It turns text prompts into interactive 720p environments that can be navigated in real time at 24 frames per second, and was released as a limited research preview.

Agents & tool useGenerative modelsSimulation

Baichuan-M2 is an open-source medical-enhanced model with 32 billion parameters, built on Qwen2.5-32B and released under Apache 2.0 for research and reference.

Large language modelsOpen sourceChina

HunyuanWorld 1.0 is Tencent's open-source model for generating explorable, mesh-exportable 3D worlds from text or images. Released in July 2025, it was followed by a series of lighter and faster versions.

Open sourceChinaGenerative models

Skild Brain is Skild AI's general-purpose foundation model for robots, trained in a universe of 100,000 different machines and meant to be fitted to existing hardware rather than built for one task.

EnterpriseDeep learningFoundation models

Aurora is a foundation model for the Earth system, trained on more than a million hours of geophysical data. It outperforms operational forecasts for weather, air quality, ocean waves and tropical cyclone tracks at far lower computational cost.

Deep learningFoundation modelsScience

Isaac GR00T N1 is an open foundation model for humanoid robots that NVIDIA announced on 18 March 2025. It is designed to be post-trained for a specific robot or task, and it pairs a planning model with quick motion control.

Open sourceFoundation modelsRobotics

Baichuan-M1 is Baichuan's medical model line, released on 24 January 2025 with Baichuan-M1-preview and the open Baichuan-M1-14B, which Baichuan described as trained from scratch for medicine.

Large language modelsOpen sourceChina

NVIDIA Cosmos is a platform of world foundation models that generate physics-based video to train robots and autonomous vehicles, released as open-weight models in January 2025.

Open sourceFoundation modelsRobotics

Genie 2 is a foundation world model from Google DeepMind, announced on 4 December 2024, that turns a single prompt image into a playable 3D environment that a person or an AI agent can explore with keyboard and mouse controls.

Agents & tool useGenerative modelsSimulation

ESM3 is a protein generative model announced by EvolutionaryScale in June 2024 that reasons over sequence, structure and function together, and generated a fluorescent protein estimated to sit over 500 million years of evolution away from known ones.

Open sourceFoundation modelsGenerative models

Octo is an open-source generalist robot policy: a transformer-based diffusion model trained on 800,000 robot trajectories that can drive a range of robots out of the box and be fine-tuned to new setups.

Open sourceDeep learningFoundation models

A Google DeepMind generative world model with 11 billion parameters that turns text, images or sketches into controllable virtual worlds, described as the first generative interactive environment trained on unlabelled internet videos without action labels.

Research historyGenerative modelsSimulation

Baichuan 3 is a closed language model with more than one hundred billion parameters, released by Baichuan on 29 January 2024. The company reported that it matched or beat GPT-4 on several Chinese benchmarks and on Chinese medical tasks.

Large language modelsChinaFoundation models

GraphCast is a Google DeepMind machine-learning model that makes global weather forecasts up to 10 days ahead, producing a 10-day forecast in under a minute on a single TPU and outperforming ECMWF's HRES on most tested variables.

Open sourceDeep learningScience

Pangu-Weather is a three-dimensional deep-learning model for medium-range global weather forecasting, published in Nature in 2023; on reanalysis data it produced stronger forecasts than ECMWF's operational system across all tested variables.

ChinaDeep learningScience

A pair of medical question-answering language models described in arXiv papers of 26 December 2022 and 16 May 2023; the first introduced the MultiMedQA benchmark, and Med-PaLM 2 reached up to 86.5% on MedQA.

Large language modelsSafety & governanceScience

RoseTTAFold is a three-track neural network for protein structure prediction, published by the Baker lab in 2021; its accuracy approached AlphaFold2's at CASP14, it models protein–protein complexes from sequence alone, and it is distributed as open code with a public web server.

Research historyOpen sourceDeep learning

AlphaFold2 is DeepMind's protein structure prediction system, announced in 2020. It reached accuracy competitive with experimental methods in many cases, and work in this area received half of the 2024 Nobel Prize in Chemistry.

Research historyDeep learningScience

MuZero is a DeepMind reinforcement-learning algorithm that pairs tree-based search with a learned model. It reached superhuman play in Atari, Go, chess and shogi without being given the environment's rules.

Research historyDeep learningReasoning

AlphaStar is a DeepMind system that plays StarCraft II. In 2019 it reached Grandmaster level with all three races, ranking above 99.8% of active players on Battle.net.

Research historyDeep learningReasoning

DeepMind's first protein-structure prediction system, which placed first overall in the 2018 CASP13 blind assessment by estimating probability distributions of distances between residues.

Research historyDeep learningScience