Models

Nemotron 3.5 Transcribe is Nvidia's free, open-weight speech transcription model, released on 28 October 2026. It handles recordings up to an hour long, transcribes up to 40 languages and can separate up to eight speakers.

Open sourceMultimodalHardware & compute

A large language model released by iFlytek on 11 February 2026, trained entirely on domestic computing power and aimed at practical use in education, healthcare, automotive and agents.

Large language modelsChinaEnterprise

Baichuan-M3 is a new-generation open-source medical-enhanced language model with 235 billion parameters, built on Qwen3-235B-A22B and released under Apache 2.0 in January 2026.

Large language modelsOpen sourceChina

Three small dense models from Mistral AI — 3B, 8B and 14B — released in December 2025 under Apache 2.0, each in base, instruct and reasoning variants with image understanding.

Large language modelsOpen sourceMultimodal

iFlytek's Spark X1.5 is a deep reasoning model released in November 2025 that runs on a domestic computing platform built with Huawei, using a 293-billion-parameter mixture-of-experts design.

Large language modelsChinaReasoning

An experimental DeepSeek model released on 29 September 2025 that introduced DeepSeek Sparse Attention to make long-context training and inference cheaper, shipped with open weights and an immediate API price cut.

Large language modelsOpen sourceChina

GLM-4.6 is an open-weights large language model released by Zhipu in late September 2025, with a 200K-token context window, about 357 billion parameters and an MIT licence, aimed at coding, reasoning and agent work.

Large language modelsOpen sourceChina

Baichuan-M2 is an open-source medical-enhanced model with 32 billion parameters, built on Qwen2.5-32B and released under Apache 2.0 for research and reference.

Large language modelsOpen sourceChina

Step 3 is StepFun's open multimodal reasoning model, with 321 billion total parameters and 38 billion active per token. It was released in July 2025 and uses Apache 2.0.

Open sourceChinaMultimodal

Baichuan-M1 is Baichuan's medical model line, released on 24 January 2025 with Baichuan-M1-preview and the open Baichuan-M1-14B, which Baichuan described as trained from scratch for medicine.

Large language modelsOpen sourceChina

iFlytek Spark X1 is a Chinese deep-reasoning model released in January 2025 and trained entirely on domestic computing hardware, with later upgrades benchmarked against OpenAI's reasoning models.

Large language modelsChinaReasoning

Ministral 3B and Ministral 8B are two small Mistral AI language models released on 16 October 2024 for on-device and edge use, offering long context, low API prices and, for the 3B, performance Mistral claimed beat its earlier 7B model.

Large language modelsEnterpriseHardware & compute

Mistral NeMo is a 12-billion-parameter language model released by Mistral AI with NVIDIA in July 2024, notable for a 128K-token context window, a new multilingual tokenizer called Tekken, and an Apache 2.0 release.

Large language modelsOpen sourceHardware & compute

iFlytek's large language model released on 27 June 2024 and trained entirely on a domestic platform co-built with Huawei; iFlytek presented it as reaching GPT-4 level while acknowledging weaker coding and multimodal abilities.

Large language modelsChinaFoundation models

ESM3 is a protein generative model announced by EvolutionaryScale in June 2024 that reasons over sequence, structure and function together, and generated a fluorescent protein estimated to sit over 500 million years of evolution away from known ones.

Open sourceFoundation modelsGenerative models

Spark V3.5 is a large language model that iFlytek released on 30 January 2024. It was the first Spark model trained entirely on the domestic FlyingStar One computing platform, and iFlytek compared it with GPT-4 Turbo.

Large language modelsChinaFoundation models

Baichuan 3 is a closed language model with more than one hundred billion parameters, released by Baichuan on 29 January 2024. The company reported that it matched or beat GPT-4 on several Chinese benchmarks and on Chinese medical tasks.

Large language modelsChinaFoundation models

A pair of medical question-answering language models described in arXiv papers of 26 December 2022 and 16 May 2023; the first introduced the MultiMedQA benchmark, and Med-PaLM 2 reached up to 86.5% on MedQA.

Large language modelsSafety & governanceScience

Megatron-Turing NLG 530B is a 530-billion-parameter language model announced by NVIDIA and Microsoft on 11 October 2021, then the largest monolithic transformer language model, trained on NVIDIA's Selene supercomputer with Megatron-LM and DeepSpeed combined.

Large language modelsFoundation modelsHardware & compute

RoseTTAFold is a three-track neural network for protein structure prediction, published by the Baker lab in 2021; its accuracy approached AlphaFold2's at CASP14, it models protein–protein complexes from sequence alone, and it is distributed as open code with a public web server.

Research historyOpen sourceDeep learning

AlphaFold2 is DeepMind's protein structure prediction system, announced in 2020. It reached accuracy competitive with experimental methods in many cases, and work in this area received half of the 2024 Nobel Prize in Chemistry.

Research historyDeep learningScience

DeepMind's first protein-structure prediction system, which placed first overall in the 2018 CASP13 blind assessment by estimating probability distributions of distances between residues.

Research historyDeep learningScience

IBM's chess computer that in May 1997 became the first computer system to defeat a reigning world chess champion in a match under standard tournament time controls.

Research historyProduct historyHardware & compute