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Papers that changed AI, with a plain-language explainer for each.
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- 2026
Muse Spark Safety & Preparedness Report
arXiv
Meta's safety and preparedness report for Muse Spark, the model behind Meta AI, sets out the catastrophic-risk evaluations behind its launch and argues that, with mitigations applied, residual risk is acceptable.
- 2024
FrontierMath: A Benchmark for Evaluating Advanced Mathematical Reasoning in AI
arXiv
FrontierMath is a benchmark of hundreds of original, unpublished mathematics problems written and vetted by expert mathematicians, introduced by Epoch AI to test advanced mathematical reasoning in AI. At release, state-of-the-art models solved under 2% of the problems.[^1][^2]
- 2024
FlashAttention-3: Fast and Accurate Attention with Asynchrony and Low-precision
arXiv
FlashAttention-3 is an attention algorithm for NVIDIA Hopper (H100) GPUs that reaches up to 75% utilization in FP16 and close to 1.2 PFLOPs/s in FP8, using asynchronous execution and low-precision techniques.
- 2024
Accurate structure prediction of biomolecular interactions with AlphaFold 3
Nature
AlphaFold 3, published in Nature in May 2024, extends structure prediction to biomolecular interactions, reporting greater accuracy than docking tools for protein–ligand binding and than AlphaFold-Multimer v.2.3 for antibody–antigen complexes.
- 2023
Scaling deep learning for materials discovery
Nature
A 2023 Nature paper from researchers at Google DeepMind presenting a scaled-up deep-learning approach to predicting stable crystal structures, screening 2.2 million candidates and reporting a large jump in stability-prediction accuracy.
- 2023
GPQA: A Graduate-Level Google-Proof Q&A Benchmark
arXiv
GPQA is a benchmark of 448 expert-written multiple-choice questions in biology, physics and chemistry, built so that skilled non-experts cannot look the answers up, and hard enough that the strongest GPT-4 baseline scored 39% while domain experts reached 65%.
- 2023
FlashAttention-2: Faster Attention with Better Parallelism and Work Partitioning
arXiv
FlashAttention-2 is a 2023 revision of the FlashAttention attention kernel that reorganizes work across GPU thread blocks and warps, roughly doubling speed and reaching up to 73% of the A100's theoretical peak throughput.
- 2023
QLoRA: Efficient Finetuning of Quantized LLMs
arXiv
QLoRA is a finetuning method that trains a 65B-parameter language model on a single 48GB GPU while matching full 16-bit finetuning quality, using 4-bit quantization, double quantization and paged optimizers.
- 2022
Learning skillful medium-range global weather forecasting
Science
GraphCast is a graph neural network trained on four decades of reanalysis data that produces 10-day global weather forecasts at 0.25 degree resolution in under a minute, outperforming the leading operational deterministic systems on most verification targets.
- 2022
Constitutional AI: Harmlessness from AI Feedback
arXiv
Constitutional AI, a 2022 paper from Anthropic, proposes training a harmless AI assistant with AI-generated feedback guided by a written set of principles, instead of human labels of harmful outputs.
- 2022
Holistic Evaluation of Language Models (HELM)
arXiv
A 2022 paper by Percy Liang, Rishi Bommasani, Tony Lee and many co-authors that ran 30 language models through the same 42 scenarios and seven metrics, turning scattered benchmarks into one standardized evaluation.
- 2022
FlashAttention: Fast and Memory-Efficient Exact Attention with IO-Awareness
arXiv
FlashAttention is an exact attention algorithm built around GPU memory traffic: by tiling computation so intermediates stay on chip, it cuts reads and writes to high bandwidth memory, training Transformers faster and enabling longer sequences.
- 2022
Training language models to follow instructions with human feedback (InstructGPT)
NeurIPS
InstructGPT used human-written demonstrations, human rankings of outputs and reinforcement learning to make GPT-3 follow user instructions better. Labelers preferred its outputs even though it was far smaller than GPT-3.
- 2022
Magnetic control of tokamak plasmas through deep reinforcement learning
Nature
A 2022 Nature paper by Degrave, Felici and colleagues showing that a deep reinforcement learning controller can learn on its own to command all of a tokamak's magnetic control coils, producing and holding a range of plasma shapes.
- 2021
Highly accurate protein structure prediction with AlphaFold
Nature
The Nature paper described AlphaFold's methods, system design, and evaluation for protein-structure prediction.
- 2021
LoRA: Low-Rank Adaptation of Large Language Models
arXiv
LoRA is a fine-tuning method that freezes a pre-trained model's weights and trains small low-rank matrices injected into each layer, cutting trainable parameters and memory by orders of magnitude.
- 2021
On the Dangers of Stochastic Parrots: Can Language Models Be Too Big?
FAccT '21
A 2021 FAccT paper by Bender, Gebru, McMillan-Major and Shmitchell that asks whether language models can be too large and sets out recommendations on costs, data, research goals and alternative directions.
- 2020
GShard: Scaling Giant Models with Conditional Computation and Automatic Sharding
arXiv
GShard, submitted to arXiv in June 2020, is a set of annotation APIs and an XLA compiler extension from Google that lets existing model code express parallel computation, scaling a sparsely gated mixture-of-experts translation model past 600 billion parameters.
- 2019
Mastering Atari, Go, chess and shogi by planning with a learned model
Nature
MuZero is a DeepMind reinforcement-learning algorithm that learns a model of its environment and plans inside that model, mastering Atari, Go, chess and shogi without being given the rules of those games.
- 2019
Language Models are Unsupervised Multitask Learners (GPT-2)
OpenAI
OpenAI's 2019 paper on GPT-2, a 1.5-billion-parameter Transformer trained on web text. It showed that a model trained only to predict the next word could perform several tasks when prompted, and its staged release sparked public debate.