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Papers that changed AI, with a plain-language explainer for each.

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  1. 2024

    FrontierMath: A Benchmark for Evaluating Advanced Mathematical Reasoning in AI

    arXiv

    FrontierMath is a benchmark of hundreds of original, unpublished mathematics problems written and vetted by expert mathematicians, introduced by Epoch AI to test advanced mathematical reasoning in AI. At release, state-of-the-art models solved under 2% of the problems.[^1][^2]

    Research historyReasoningScience

  2. 2024

    FlashAttention-3: Fast and Accurate Attention with Asynchrony and Low-precision

    arXiv

    FlashAttention-3 is an attention algorithm for NVIDIA Hopper (H100) GPUs that reaches up to 75% utilization in FP16 and close to 1.2 PFLOPs/s in FP8, using asynchronous execution and low-precision techniques.

    Research historyDeep learningDeveloper tools

  3. 2024

    Transformers are SSMs: Generalized Models and Efficient Algorithms Through Structured State Space Duality

    ICML

    Tri Dao and Albert Gu's paper introduces state space duality, a framework showing that structured state space models and attention variants are closely related, and uses it to derive Mamba-2, whose core layer runs 2 to 8 times faster than Mamba's.

    Research historyDeep learningTransformers & attention

  4. 2024

    Accurate structure prediction of biomolecular interactions with AlphaFold 3

    Nature

    AlphaFold 3, published in Nature in May 2024, extends structure prediction to biomolecular interactions, reporting greater accuracy than docking tools for protein–ligand binding and than AlphaFold-Multimer v.2.3 for antibody–antigen complexes.

    Deep learningScienceBiomedicine

  5. 2023

    Scaling deep learning for materials discovery

    Nature

    A 2023 Nature paper from researchers at Google DeepMind presenting a scaled-up deep-learning approach to predicting stable crystal structures, screening 2.2 million candidates and reporting a large jump in stability-prediction accuracy.

    Deep learningData & datasetsScience

  6. 2023

    GPQA: A Graduate-Level Google-Proof Q&A Benchmark

    arXiv

    GPQA is a benchmark of 448 expert-written multiple-choice questions in biology, physics and chemistry, built so that skilled non-experts cannot look the answers up, and hard enough that the strongest GPT-4 baseline scored 39% while domain experts reached 65%.

    Research historyReasoningScience

  7. 2023

    FlashAttention-2: Faster Attention with Better Parallelism and Work Partitioning

    arXiv

    FlashAttention-2 is a 2023 revision of the FlashAttention attention kernel that reorganizes work across GPU thread blocks and warps, roughly doubling speed and reaching up to 73% of the A100's theoretical peak throughput.

    Research historyDeep learningDeveloper tools

  8. 2023

    QLoRA: Efficient Finetuning of Quantized LLMs

    arXiv

    QLoRA is a finetuning method that trains a 65B-parameter language model on a single 48GB GPU while matching full 16-bit finetuning quality, using 4-bit quantization, double quantization and paged optimizers.

    Large language modelsResearch historyDeveloper tools

  9. 2022

    Learning skillful medium-range global weather forecasting

    Science

    GraphCast is a graph neural network trained on four decades of reanalysis data that produces 10-day global weather forecasts at 0.25 degree resolution in under a minute, outperforming the leading operational deterministic systems on most verification targets.

    Deep learningScienceSimulation

  10. 2022

    Scalable Diffusion Models with Transformers (DiT)

    arXiv

    A 2022 paper by William Peebles and Saining Xie that replaces the U-Net backbone of diffusion models with a transformer operating on latent patches, showing that image quality improves predictably as compute grows and reaching a state-of-the-art FID of 2.27 on ImageNet 256×256.

    Research historyGenerative modelsImage generation

  11. 2022

    FlashAttention: Fast and Memory-Efficient Exact Attention with IO-Awareness

    arXiv

    FlashAttention is an exact attention algorithm built around GPU memory traffic: by tiling computation so intermediates stay on chip, it cuts reads and writes to high bandwidth memory, training Transformers faster and enabling longer sequences.

    Research historyDeep learningDeveloper tools

  12. 2022

    Magnetic control of tokamak plasmas through deep reinforcement learning

    Nature

    A 2022 Nature paper by Degrave, Felici and colleagues showing that a deep reinforcement learning controller can learn on its own to command all of a tokamak's magnetic control coils, producing and holding a range of plasma shapes.

    Deep learningHardware & computeScience

  13. 2021

    Highly accurate protein structure prediction with AlphaFold

    Nature

    The Nature paper described AlphaFold's methods, system design, and evaluation for protein-structure prediction.

    Research historyScienceBiomedicine

  14. 2021

    LoRA: Low-Rank Adaptation of Large Language Models

    arXiv

    LoRA is a fine-tuning method that freezes a pre-trained model's weights and trains small low-rank matrices injected into each layer, cutting trainable parameters and memory by orders of magnitude.

    Large language modelsResearch historyDeveloper tools

  15. 2020

    An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale (ViT)

    arXiv

    A 2020 paper showing that a plain Transformer applied directly to sequences of image patches, with no convolution at all, can match state-of-the-art convolutional networks on image classification.

    Research historyDeep learningComputer vision

  16. 2020

    An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale

    arXiv 2010.11929 (ICLR 2021)

    A 2020 paper by Alexey Dosovitskiy and colleagues showing that a pure Transformer applied directly to sequences of image patches — the Vision Transformer, or ViT — matches state-of-the-art convolutional networks on image classification when pre-trained on large amounts of data.

    Research historyComputer visionTransformers & attention

  17. 2020

    GShard: Scaling Giant Models with Conditional Computation and Automatic Sharding

    arXiv

    GShard, submitted to arXiv in June 2020, is a set of annotation APIs and an XLA compiler extension from Google that lets existing model code express parallel computation, scaling a sparsely gated mixture-of-experts translation model past 600 billion parameters.

    Large language modelsResearch historyDeveloper tools

  18. 2019

    Mastering Atari, Go, chess and shogi by planning with a learned model

    Nature

    MuZero is a DeepMind reinforcement-learning algorithm that learns a model of its environment and plans inside that model, mastering Atari, Go, chess and shogi without being given the rules of those games.

    Research historyDeep learningScience

  19. 2019

    Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformer (T5)

    JMLR

    A 2019 Google paper that frames every language task as text in, text out, using one encoder-decoder Transformer and one training setup. It also introduced the C4 dataset, and the released T5 models became common research starting points.

    Large language modelsOpen sourceData & datasets

  20. 2018

    BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding

    NAACL

    Google's 2018 BERT paper introduced an encoder-only Transformer that reads text in both directions and is pre-trained by hiding words. It set new results on eleven language tasks and made download-and-fine-tune the default workflow.

    Large language modelsResearch historyFoundation models