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Papers that changed AI, with a plain-language explainer for each.
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- 2025
ARC-AGI-2: A New Challenge for Frontier AI Reasoning Systems
arXiv
A 2025 paper introducing ARC-AGI-2, a benchmark of input-output puzzle tasks built to measure abstract reasoning in frontier AI systems, with human testing as a baseline and a task set designed to give a more granular signal of progress.
- 2024
FrontierMath: A Benchmark for Evaluating Advanced Mathematical Reasoning in AI
arXiv
FrontierMath is a benchmark of hundreds of original, unpublished mathematics problems written and vetted by expert mathematicians, introduced by Epoch AI to test advanced mathematical reasoning in AI. At release, state-of-the-art models solved under 2% of the problems.[^1][^2]
- 2024
SAM 2: Segment Anything in Images and Videos
arXiv
SAM 2 is a Meta FAIR foundation model that segments objects in images and videos from simple prompts such as points, boxes or masks, released together with a large video segmentation dataset and training code.
- 2024
Accurate structure prediction of biomolecular interactions with AlphaFold 3
Nature
AlphaFold 3, published in Nature in May 2024, extends structure prediction to biomolecular interactions, reporting greater accuracy than docking tools for protein–ligand binding and than AlphaFold-Multimer v.2.3 for antibody–antigen complexes.
- 2023
Scaling deep learning for materials discovery
Nature
A 2023 Nature paper from researchers at Google DeepMind presenting a scaled-up deep-learning approach to predicting stable crystal structures, screening 2.2 million candidates and reporting a large jump in stability-prediction accuracy.
- 2023
GPQA: A Graduate-Level Google-Proof Q&A Benchmark
arXiv
GPQA is a benchmark of 448 expert-written multiple-choice questions in biology, physics and chemistry, built so that skilled non-experts cannot look the answers up, and hard enough that the strongest GPT-4 baseline scored 39% while domain experts reached 65%.
- 2023
Segment Anything
arXiv 2304.02643
A 2023 paper that introduces the Segment Anything project: a promptable segmentation task, a model, and a dataset of over 1 billion masks on 11 million images, all released to advance foundation models for computer vision.
- 2022
Learning skillful medium-range global weather forecasting
Science
GraphCast is a graph neural network trained on four decades of reanalysis data that produces 10-day global weather forecasts at 0.25 degree resolution in under a minute, outperforming the leading operational deterministic systems on most verification targets.
- 2022
Magnetic control of tokamak plasmas through deep reinforcement learning
Nature
A 2022 Nature paper by Degrave, Felici and colleagues showing that a deep reinforcement learning controller can learn on its own to command all of a tokamak's magnetic control coils, producing and holding a range of plasma shapes.
- 2021
Highly accurate protein structure prediction with AlphaFold
Nature
The Nature paper described AlphaFold's methods, system design, and evaluation for protein-structure prediction.
- 2021
Learning Transferable Visual Models From Natural Language Supervision (CLIP)
ICML
CLIP is an OpenAI model trained on 400 million image-text pairs to map pictures and sentences into one shared space, so it can classify images zero-shot from a written description.
- 2020
An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale (ViT)
arXiv
A 2020 paper showing that a plain Transformer applied directly to sequences of image patches, with no convolution at all, can match state-of-the-art convolutional networks on image classification.
- 2020
An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale
arXiv 2010.11929 (ICLR 2021)
A 2020 paper by Alexey Dosovitskiy and colleagues showing that a pure Transformer applied directly to sequences of image patches — the Vision Transformer, or ViT — matches state-of-the-art convolutional networks on image classification when pre-trained on large amounts of data.
- 2020
NeRF: Representing Scenes as Neural Radiance Fields for View Synthesis
arXiv
A 2020 paper by Mildenhall, Srinivasan, Tancik, Barron, Ramamoorthi and Ng that represents a scene as a neural radiance field: a network mapping 5D coordinates to density and colour, optimized from a sparse set of images with known camera poses.
- 2020
Scaling Laws for Neural Language Models
arXiv
A 2020 paper finding that language model loss falls predictably, as a power law, with model size, data and compute. It gave labs a quantitative reason to build much larger models and shaped the scale-up that followed.
- 2019
Mastering Atari, Go, chess and shogi by planning with a learned model
Nature
MuZero is a DeepMind reinforcement-learning algorithm that learns a model of its environment and plans inside that model, mastering Atari, Go, chess and shogi without being given the rules of those games.
- 2019
On the Measure of Intelligence (ARC-AGI)
arXiv
A 2019 paper by Francois Chollet that defines intelligence as skill-acquisition efficiency and introduces the Abstraction and Reasoning Corpus (ARC), a benchmark of grid tasks that assumes no specialised knowledge or language.
- 2019
Megatron-LM: Training Multi-Billion Parameter Language Models Using Model Parallelism
arXiv 1909.08053
An NVIDIA paper from 2019 presenting an intra-layer model parallelism method, implemented with a few communication operations in native PyTorch, that trained transformer models of up to 8.3 billion parameters and improved several benchmarks.
- 2018
A Style-Based Generator Architecture for Generative Adversarial Networks
arXiv
This 2018 paper introduces a style-based GAN generator that separates high-level attributes from stochastic variation and allows scale-specific control, improving distribution quality, interpolation, and disentanglement.
- 2018
Large Scale GAN Training for High Fidelity Natural Image Synthesis
arXiv
A 2018 paper by Andrew Brock, Jeff Donahue and Karen Simonyan that trained generative adversarial networks at the largest scale attempted at the time, introduced BigGANs and set a new state of the art in class-conditional image synthesis.