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Foundation, generative, multimodal and specialised models.

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2026

  • Apr 2, 2026 MAI-Transcribe-1

    A speech-to-text model from Microsoft AI released in April 2026 that transcribes 25 languages, runs Copilot's Voice Mode, and starts at $0.36 per hour of audio.

    EnterpriseMultimodalCloud

  • Jan 13, 2026 Baichuan-M3

    Baichuan-M3 is a new-generation open-source medical-enhanced language model with 235 billion parameters, built on Qwen3-235B-A22B and released under Apache 2.0 in January 2026.

    Large language modelsOpen sourceChina

2025

2024

  • Dec 12, 2024 Phi-4

    Phi-4 is Microsoft's 14-billion-parameter dense decoder-only language model, built with a data-quality-first recipe heavy on synthetic data and released with full weights under the MIT licence in January 2025.

    Large language modelsOpen sourceReasoning

  • Dec 3, 2024 Amazon Nova

    Amazon Nova is Amazon's family of foundation models, introduced on 3 December 2024 and offered exclusively in Amazon Bedrock. It spans text understanding models from Micro to Pro, plus Canvas for images and Reel for video, and was succeeded by Nova 2 in December 2025.

    Large language modelsEnterpriseMultimodal

  • Nov 26, 2024 OLMo 2

    OLMo 2 is the second generation of the Allen Institute for AI's fully open language model family, released in 7B and 13B sizes with weights, data, code and training recipes all public.

    Large language modelsOpen sourceData & datasets

  • Nov 2024 SmolLM2

    SmolLM2 is Hugging Face's second family of small language models, released in November 2024 at 135M, 360M and 1.7B parameters, with open weights and a data-centric training recipe.

    Large language modelsOpen sourceConsumer apps

  • Sep 25, 2024 Molmo

    Molmo is a family of open vision-language models released by Ai2 on 25 September 2024 that can point at objects in images, with weights, code, data and evaluations published openly.

    Open sourceMultimodalData & datasets

  • Sep 5, 2024 Hunyuan Turbo

    Hunyuan Turbo is Tencent's large language model, released on Tencent Cloud in September 2024 and tuned for lower training and serving costs. It was succeeded in February 2025 by Hunyuan Turbo S, which cut API prices further.

    Large language modelsChinaEnterprise

  • Jul 29, 2024 SAM 2 (Segment Anything Model 2)

    SAM 2 is Meta's 2024 successor to the Segment Anything Model. It segments objects in both images and videos in real time, and its release included the SA-V video dataset.

    Open sourceFoundation modelsData & datasets

  • Jul 16, 2024 SmolLM

    SmolLM is a family of small language models with 135M, 360M and 1.7B parameters, released openly by Hugging Face in July 2024 for on-device use and trained on a purpose-built corpus of generated textbooks, code and filtered web text.

    Large language modelsOpen sourceConsumer apps

  • Jun 25, 2024 ESM3

    ESM3 is a protein generative model announced by EvolutionaryScale in June 2024 that reasons over sequence, structure and function together, and generated a fluorescent protein estimated to sit over 500 million years of evolution away from known ones.

    Open sourceFoundation modelsGenerative models

  • Jun 14, 2024 Nemotron-4 340B

    Nemotron-4 340B is a family of open models from NVIDIA, released on 14 June 2024 as base, instruct and reward models. It was built to generate synthetic data for training other language models, and it fits on a single eight-GPU DGX H100.

    Large language modelsOpen sourceEnterprise

  • May 15, 2024 Doubao model family (Doubao Pro, 2024)

    ByteDance's Doubao model family, launched through Volcano Engine in May 2024, offered general-purpose, speech and image models at prices far below rivals, helping set off a price war among Chinese providers.

    Large language modelsChinaEnterprise

  • May 8, 2024 AlphaFold 3

    AlphaFold 3 is a structure-prediction model from Google DeepMind and Isomorphic Labs, announced on 8 May 2024. It predicts the structures and interactions of proteins, DNA, RNA, ligands and chemical modifications, extending structure prediction beyond proteins alone.[^1]

    Deep learningGenerative modelsScience

  • Apr 22, 2024 OpenELM

    OpenELM is a family of small open language models from Apple, published in four sizes from 270M to 3B parameters with its training framework, logs, checkpoints and MLX conversion code.

    Large language modelsResearch historyOpen source

  • Apr 4, 2024 Command R+

    Cohere's 104-billion-parameter language model, announced in April 2024, is tuned for retrieval-augmented generation and multi-step tool use in business settings; it launched first on Microsoft Azure and was also released as open weights.

    Large language modelsEnterpriseAgents & tool use

  • Feb 28, 2024 StarCoder2

    StarCoder2 is a family of open code models in 3B, 7B and 15B sizes, released in February 2024 by BigCode (Hugging Face and ServiceNow) with NVIDIA and trained on The Stack v2, published together with its dataset and training code.

    Large language modelsOpen sourceData & datasets

  • Feb 26, 2024 Mistral Large

    Mistral Large is the French company Mistral AI's first flagship proprietary large language model, released on 26 February 2024 with a 32K-token context window, native fluency in five languages, and built-in function calling and JSON output.

    Large language modelsEnterpriseCloud

  • Feb 1, 2024 OLMo

    OLMo is the Allen Institute for AI's open language model, released on 1 February 2024 in 1B and 7B sizes with its Dolma training data, training code, logs and checkpoints, all under Apache 2.0.

    Large language modelsResearch historyOpen source

  • Feb 2024 Aya 101

    Aya 101 is a 13-billion-parameter, instruction-tuned language model from Cohere For AI that follows instructions in 101 languages. It was released under Apache 2.0 in February 2024.

    Large language modelsOpen sourceFoundation models

  • Jan 29, 2024 Baichuan 3

    Baichuan 3 is a closed language model with more than one hundred billion parameters, released by Baichuan on 29 January 2024. The company reported that it matched or beat GPT-4 on several Chinese benchmarks and on Chinese medical tasks.

    Large language modelsChinaFoundation models

2023

2022

2021

  • Jul 15, 2021 RoseTTAFold

    RoseTTAFold is a three-track neural network for protein structure prediction, published by the Baker lab in 2021; its accuracy approached AlphaFold2's at CASP14, it models protein–protein complexes from sequence alone, and it is distributed as open code with a public web server.

    Research historyOpen sourceDeep learning

2020

  • Nov 30, 2020 AlphaFold2

    AlphaFold2 is DeepMind's protein structure prediction system, announced in 2020. It reached accuracy competitive with experimental methods in many cases, and work in this area received half of the 2024 Nobel Prize in Chemistry.

    Research historyDeep learningScience

2019

2018

2011

  • Feb 2011 IBM Watson

    IBM Watson is a question-answering computer system built by an IBM research team led by David Ferrucci; in February 2011 it defeated the two foremost all-time champions of the televised quiz show Jeopardy!

    Research historyEnterpriseReasoning