Models

Claude Fable 5.1, released on 1 September 2026, keeps the $10 and $50 per million token price of Fable 5, with cache reads 75% cheaper. Its sibling Claude Mythos 5.1 is limited to trusted-access programmes.

Large language modelsAgents & tool useSafety & governance

Claude Opus 5, released on 24 July 2026 at $5 and $25 per million tokens, is Anthropic's most aligned model to date and its most capable generally available model for scientific research.

Large language modelsAgents & tool useSafety & governance

Claude Fable 5 is Anthropic's Mythos-class model for general use, released on 9 June 2026. Its sibling Claude Mythos 5 is the same model with some safeguards lifted for vetted users.

Large language modelsAgents & tool useSafety & governance

A speech-to-text model from Microsoft AI released in April 2026 that transcribes 25 languages, runs Copilot's Voice Mode, and starts at $0.36 per hour of audio.

EnterpriseMultimodalCloud

Gemini 3 Deep Think is Google's enhanced reasoning mode for Gemini 3, announced with Gemini 3 Pro on 18 November 2025 and released to Google AI Ultra subscribers on 3 December 2025, with an upgraded version following in February 2026.

Large language modelsReasoningScience

Amazon Nova 2 is the second generation of Amazon's Nova models, released at AWS re:Invent in December 2025. Its first member, Nova 2 Lite, is a fast reasoning model available in Amazon Bedrock with a 1-million-token context.

Large language modelsAgents & tool useMultimodal

DeepSeekMath-V2, released on 27 November 2025, is a mathematical reasoning model trained to verify its own proofs. DeepSeek reported gold-level scores on IMO 2025 and CMO 2024 problems, and 118 of 120 on Putnam 2024.

Open sourceChinaReasoning

Qwen3-Max is Alibaba's proprietary trillion-parameter language model, released in September 2025 and served through Alibaba's API. It is the Max-tier flagship that followed Qwen2.5-Max.

Large language modelsChinaFoundation models

An enhanced reasoning mode for Gemini 2.5 Pro that weighs multiple hypotheses in parallel before answering, announced experimentally in 2025 and known for reaching gold-medal standard at the International Mathematical Olympiad.

Large language modelsReasoningScience

OpenAI o3-pro is a version of the o3 model released on 10 June 2025, which OpenAI described as its most capable model at the time and recommended for hard questions where reliability matters more than speed.

Large language modelsReasoningScience

Aurora is a foundation model for the Earth system, trained on more than a million hours of geophysical data. It outperforms operational forecasts for weather, air quality, ocean waves and tropical cyclone tracks at far lower computational cost.

Deep learningFoundation modelsScience

AlphaEvolve is a Google DeepMind coding agent announced on 14 May 2025 that pairs Gemini models with automated evaluators to evolve algorithms, yielding a Borg scheduling heuristic, faster kernels and new mathematical results.

Agents & tool useReasoningScience

DeepSeek's open-source model for formal theorem proving in Lean 4, trained with a subgoal-decomposition pipeline; it reached an 88.9% pass ratio on MiniF2F-test and introduced the ProverBench benchmark.

Open sourceChinaReasoning

Amazon Nova Premier is the most capable model of the first Nova generation, available in Amazon Bedrock from 30 April 2025. It handles text, images and video with a 1-million-token context window, and also serves as a teacher model for smaller Nova models.

Large language modelsEnterpriseMultimodal

A speech-to-speech foundation model in Amazon's Nova family, announced on 8 April 2025, which handles recognition, understanding and speech generation in a single model rather than a chain of separate ones.

Agents & tool useMultimodalGenerative models

Hunyuan-T1 is Tencent's deep-reasoning model, officially released on 21 March 2025 and built on the Hunyuan-TurboS base. Tencent did not release its weights.

Large language modelsChinaReasoning

Hunyuan Turbo S is a fast-thinking model released by Tencent on 27 February 2025, built on a hybrid Mamba-Transformer design with 560 billion total parameters. Its weights were not released.

Large language modelsChinaFoundation models

Qwen2.5-Max is Alibaba's large mixture-of-experts model, announced in January 2025. It was offered through Qwen Chat and the Alibaba Cloud API, and its weights were not released.

Large language modelsChinaFoundation models

A version of OpenAI's o1 that spends more compute before answering, launched on 5 December 2024 inside the $200-a-month ChatGPT Pro plan and added to the API on 19 March 2025.

Large language modelsConsumer appsReasoning

Amazon Nova is Amazon's family of foundation models, introduced on 3 December 2024 and offered exclusively in Amazon Bedrock. It spans text understanding models from Micro to Pro, plus Canvas for images and Reel for video, and was succeeded by Nova 2 in December 2025.

Large language modelsEnterpriseMultimodal

Hunyuan Turbo is Tencent's large language model, released on Tencent Cloud in September 2024 and tuned for lower training and serving costs. It was succeeded in February 2025 by Hunyuan Turbo S, which cut API prices further.

Large language modelsChinaEnterprise

AlphaProof is a Google DeepMind reinforcement-learning system that proves mathematical statements in the formal language Lean. At the 2024 International Mathematical Olympiad it solved three problems, and together with AlphaGeometry 2 reached silver-medal level.

ReasoningScienceSymbolic AI

A 7-billion-parameter model released by Mistral AI on 16 July 2024 for mathematical and STEM reasoning, built on Mistral 7B, openly licensed, and now listed as deprecated.

Open sourceReasoningScience

ESM3 is a protein generative model announced by EvolutionaryScale in June 2024 that reasons over sequence, structure and function together, and generated a fluorescent protein estimated to sit over 500 million years of evolution away from known ones.

Open sourceFoundation modelsGenerative models

Cohere's 104-billion-parameter language model, announced in April 2024, is tuned for retrieval-augmented generation and multi-step tool use in business settings; it launched first on Microsoft Azure and was also released as open weights.

Large language modelsEnterpriseAgents & tool use

Mistral Large is the French company Mistral AI's first flagship proprietary large language model, released on 26 February 2024 with a 32K-token context window, native fluency in five languages, and built-in function calling and JSON output.

Large language modelsEnterpriseCloud

DeepSeekMath is a 7B-parameter open language model built for mathematical reasoning and released in 2024. It reached 51.7% on the competition-level MATH benchmark without external tools, and introduced GRPO, a reinforcement-learning algorithm that uses less memory than PPO.

Large language modelsOpen sourceChina

AlphaGeometry is a Google DeepMind system that pairs a neural language model with a symbolic deduction engine to solve olympiad geometry problems, reaching near gold-medal level on a benchmark of 30 problems.

Open sourceReasoningScience

FunSearch is a method that uses a pretrained large language model inside an evolutionary loop to search for programs that solve mathematical and computational problems, rather than for answers directly. It produced new results on the cap set problem and on online bin packing.

Deep learningReasoningScience

GNoME is a Google DeepMind deep-learning tool, announced on 29 November 2023, that predicts new inorganic crystals; it produced 2.2 million candidate structures, of which 380,000 were predicted to be stable.

Deep learningData & datasetsScience

GraphCast is a Google DeepMind machine-learning model that makes global weather forecasts up to 10 days ahead, producing a 10-day forecast in under a minute on a single TPU and outperforming ECMWF's HRES on most tested variables.

Open sourceDeep learningScience

Hunyuan is Tencent's first proprietary large foundation model, unveiled in September 2023 and offered to enterprises through Tencent Cloud. The line was later branded Hy.

Large language modelsChinaEnterprise

Pangu-Weather is a three-dimensional deep-learning model for medium-range global weather forecasting, published in Nature in 2023; on reanalysis data it produced stronger forecasts than ECMWF's operational system across all tested variables.

ChinaDeep learningScience

Amazon Titan is a family of foundation models built by Amazon for Amazon Bedrock, covering text generation, embeddings and image generation. It was announced in 2023 and later succeeded by Amazon Nova.

Large language modelsEnterpriseCloud

Pythia is a suite of 16 open language models from EleutherAI, ranging from 70 million to 12 billion parameters, all trained on the same data in the same order, with 154 public checkpoints from each training run.

Large language modelsResearch historyOpen source

A pair of medical question-answering language models described in arXiv papers of 26 December 2022 and 16 May 2023; the first introduced the MultiMedQA benchmark, and Med-PaLM 2 reached up to 86.5% on MedQA.

Large language modelsSafety & governanceScience

Galactica is a large language model for science, unveiled by Meta AI and Papers with Code in November 2022. Its public demo was taken down about three days later, after users found it produced fake papers.

Large language modelsResearch historyOpen source

RoseTTAFold is a three-track neural network for protein structure prediction, published by the Baker lab in 2021; its accuracy approached AlphaFold2's at CASP14, it models protein–protein complexes from sequence alone, and it is distributed as open code with a public web server.

Research historyOpen sourceDeep learning

AlphaFold2 is DeepMind's protein structure prediction system, announced in 2020. It reached accuracy competitive with experimental methods in many cases, and work in this area received half of the 2024 Nobel Prize in Chemistry.

Research historyDeep learningScience

DeepMind's first protein-structure prediction system, which placed first overall in the 2018 CASP13 blind assessment by estimating probability distributions of distances between residues.

Research historyDeep learningScience