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Foundation, generative, multimodal and specialised models.
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2026
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Sep 1, 2026
Claude Fable 5.1 (and Claude Mythos 5.1)
Claude Fable 5.1, released on 1 September 2026, keeps the $10 and $50 per million token price of Fable 5, with cache reads 75% cheaper. Its sibling Claude Mythos 5.1 is limited to trusted-access programmes.
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Jul 24, 2026
Claude Opus 5
Claude Opus 5, released on 24 July 2026 at $5 and $25 per million tokens, is Anthropic's most aligned model to date and its most capable generally available model for scientific research.
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Jun 9, 2026
Claude Fable 5 (and Claude Mythos 5)
Claude Fable 5 is Anthropic's Mythos-class model for general use, released on 9 June 2026. Its sibling Claude Mythos 5 is the same model with some safeguards lifted for vetted users.
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Mar 16, 2026
NVIDIA Isaac GR00T N2 (preview)
NVIDIA previewed Isaac GR00T N2, a next-generation robot foundation model built on a world action model architecture that the company says more than doubles success on new tasks compared with leading VLA models.
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Mar 16, 2026
NVIDIA Isaac GR00T N1.7
An open reasoning vision-language-action model from NVIDIA for humanoid robots, announced in March 2026 as commercially usable and trained on large public robot manipulation datasets.
2025
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Dec 3, 2025
Gemini 3 Deep Think
Gemini 3 Deep Think is Google's enhanced reasoning mode for Gemini 3, announced with Gemini 3 Pro on 18 November 2025 and released to Google AI Ultra subscribers on 3 December 2025, with an upgraded version following in February 2026.
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Nov 27, 2025
DeepSeekMath-V2
DeepSeekMath-V2, released on 27 November 2025, is a mathematical reasoning model trained to verify its own proofs. DeepSeek reported gold-level scores on IMO 2025 and CMO 2024 problems, and 118 of 120 on Putnam 2024.
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Aug 1, 2025
Gemini 2.5 Deep Think
An enhanced reasoning mode for Gemini 2.5 Pro that weighs multiple hypotheses in parallel before answering, announced experimentally in 2025 and known for reaching gold-medal standard at the International Mathematical Olympiad.
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Jun 10, 2025
OpenAI o3-pro
OpenAI o3-pro is a version of the o3 model released on 10 June 2025, which OpenAI described as its most capable model at the time and recommended for hard questions where reliability matters more than speed.
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May 21, 2025
Aurora
Aurora is a foundation model for the Earth system, trained on more than a million hours of geophysical data. It outperforms operational forecasts for weather, air quality, ocean waves and tropical cyclone tracks at far lower computational cost.
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May 14, 2025
AlphaEvolve
AlphaEvolve is a Google DeepMind coding agent announced on 14 May 2025 that pairs Gemini models with automated evaluators to evolve algorithms, yielding a Borg scheduling heuristic, faster kernels and new mathematical results.
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Apr 30, 2025
DeepSeek-Prover-V2
DeepSeek's open-source model for formal theorem proving in Lean 4, trained with a subgoal-decomposition pipeline; it reached an 88.9% pass ratio on MiniF2F-test and introduced the ProverBench benchmark.
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Apr 16, 2025
OpenAI o3
OpenAI's second-generation reasoning model, announced in December 2024 and released in April 2025, which posted large gains over o1 on science, software-engineering and competitive-programming benchmarks before being succeeded by GPT-5.
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Mar 18, 2025
NVIDIA Isaac GR00T N1
Isaac GR00T N1 is an open foundation model for humanoid robots that NVIDIA announced on 18 March 2025. It is designed to be post-trained for a specific robot or task, and it pairs a planning model with quick motion control.
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Mar 12, 2025
Gemini Robotics
Gemini Robotics is a vision-language-action model from Google DeepMind, built on Gemini 2.0, that outputs physical actions to control robots. It was announced on 12 March 2025 alongside Gemini Robotics-ER.
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Mar 10, 2025
AgiBot GO-1 (Genie Operator-1)
A general-purpose embodied foundation model released by AgiBot on 10 March 2025, built on a Vision-Language-Latent-Action architecture. In the company's tests across five tasks it raised average success rate from 46% to 78%.
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Feb 20, 2025
Figure Helix
Helix is Figure's vision-language-action model for humanoid control, pairing a 7-billion-parameter vision-language model with a fast 80-million-parameter action policy, trained on about 500 hours of teleoperated data and run entirely on onboard GPUs.
2024
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Dec 5, 2024
OpenAI o1 pro
A version of OpenAI's o1 that spends more compute before answering, launched on 5 December 2024 inside the $200-a-month ChatGPT Pro plan and added to the API on 19 March 2025.
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Sep 12, 2024
OpenAI o1
OpenAI o1 is the first reasoning model series from OpenAI, introduced in September 2024. It thinks through a long internal chain of thought before answering, and it was the base for later reasoning models such as o3.
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Jul 25, 2024
AlphaProof
AlphaProof is a Google DeepMind reinforcement-learning system that proves mathematical statements in the formal language Lean. At the 2024 International Mathematical Olympiad it solved three problems, and together with AlphaGeometry 2 reached silver-medal level.
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Jul 16, 2024
Mathstral
A 7-billion-parameter model released by Mistral AI on 16 July 2024 for mathematical and STEM reasoning, built on Mistral 7B, openly licensed, and now listed as deprecated.
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Jun 25, 2024
ESM3
ESM3 is a protein generative model announced by EvolutionaryScale in June 2024 that reasons over sequence, structure and function together, and generated a fluorescent protein estimated to sit over 500 million years of evolution away from known ones.
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May 8, 2024
AlphaFold 3
AlphaFold 3 is a structure-prediction model from Google DeepMind and Isomorphic Labs, announced on 8 May 2024. It predicts the structures and interactions of proteins, DNA, RNA, ligands and chemical modifications, extending structure prediction beyond proteins alone.[^1]
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Mar 18, 2024
Project GR00T
NVIDIA's project for a general-purpose foundation model for humanoid robots, announced in March 2024 and followed in March 2025 by Isaac GR00T N1, an open, customizable model released with training data and evaluation scenarios.
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Feb 5, 2024
DeepSeekMath
DeepSeekMath is a 7B-parameter open language model built for mathematical reasoning and released in 2024. It reached 51.7% on the competition-level MATH benchmark without external tools, and introduced GRPO, a reinforcement-learning algorithm that uses less memory than PPO.
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Jan 17, 2024
AlphaGeometry
AlphaGeometry is a Google DeepMind system that pairs a neural language model with a symbolic deduction engine to solve olympiad geometry problems, reaching near gold-medal level on a benchmark of 30 problems.
2023
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Dec 14, 2023
FunSearch
FunSearch is a method that uses a pretrained large language model inside an evolutionary loop to search for programs that solve mathematical and computational problems, rather than for answers directly. It produced new results on the cap set problem and on online bin packing.
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Nov 29, 2023
GNoME (Graph Networks for Materials Exploration)
GNoME is a Google DeepMind deep-learning tool, announced on 29 November 2023, that predicts new inorganic crystals; it produced 2.2 million candidate structures, of which 380,000 were predicted to be stable.
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Nov 14, 2023
GraphCast
GraphCast is a Google DeepMind machine-learning model that makes global weather forecasts up to 10 days ahead, producing a 10-day forecast in under a minute on a single TPU and outperforming ECMWF's HRES on most tested variables.
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Jul 5, 2023
Pangu-Weather
Pangu-Weather is a three-dimensional deep-learning model for medium-range global weather forecasting, published in Nature in 2023; on reanalysis data it produced stronger forecasts than ECMWF's operational system across all tested variables.
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Apr 3, 2023
Pythia
Pythia is a suite of 16 open language models from EleutherAI, ranging from 70 million to 12 billion parameters, all trained on the same data in the same order, with 154 public checkpoints from each training run.
2022
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Dec 26, 2022
Med-PaLM and Med-PaLM 2
A pair of medical question-answering language models described in arXiv papers of 26 December 2022 and 16 May 2023; the first introduced the MultiMedQA benchmark, and Med-PaLM 2 reached up to 86.5% on MedQA.
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Nov 15, 2022
Galactica
Galactica is a large language model for science, unveiled by Meta AI and Papers with Code in November 2022. Its public demo was taken down about three days later, after users found it produced fake papers.
2021
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Jul 15, 2021
RoseTTAFold
RoseTTAFold is a three-track neural network for protein structure prediction, published by the Baker lab in 2021; its accuracy approached AlphaFold2's at CASP14, it models protein–protein complexes from sequence alone, and it is distributed as open code with a public web server.
2020
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Nov 30, 2020
AlphaFold2
AlphaFold2 is DeepMind's protein structure prediction system, announced in 2020. It reached accuracy competitive with experimental methods in many cases, and work in this area received half of the 2024 Nobel Prize in Chemistry.
2018
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Dec 2018
AlphaFold (first version)
DeepMind's first protein-structure prediction system, which placed first overall in the 2018 CASP13 blind assessment by estimating probability distributions of distances between residues.