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Papers that changed AI, with a plain-language explainer for each.
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- 2024
Accurate structure prediction of biomolecular interactions with AlphaFold 3
Nature
AlphaFold 3, published in Nature in May 2024, extends structure prediction to biomolecular interactions, reporting greater accuracy than docking tools for protein–ligand binding and than AlphaFold-Multimer v.2.3 for antibody–antigen complexes.
- 2021
Highly accurate protein structure prediction with AlphaFold
Nature
The Nature paper described AlphaFold's methods, system design, and evaluation for protein-structure prediction.
- 2015
U-Net: Convolutional Networks for Biomedical Image Segmentation
arXiv
A convolutional network for biomedical image segmentation, posted to arXiv on May 18, 2015, that trains end to end from very few annotated images and won the ISBI cell tracking challenge 2015 in its categories.